Top 3 Rare Disease in Malaysia
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src: OfficialMRDS2025

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Marfan Syndrome
cases in Malaysia:

src: Rare Disease Malaysia 2024

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Marfan Body Map
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General General
Marfan Marfan
PWS PWS
OI OI
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Eye
Heart
Lung
Joint
Spine

Air escapes from the lung into the chest, and causes chest pain, breathing difficulty, low oxygen in body.

Spine bends more over time which causes poor posture, back pain, and difficulty breathing if severe.

Aortic dissection can cause severe internal bleeding. Enlarged aorta which makes heart works harder.

Bones in the joints move out of place which causes pain, swelling, limited movement, and long-term joint damage.

Retinal detachment which can causes vision loss.

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Medication Routine Monitoring Physical Activity Guidance Surgery
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src: Bernama, 2025

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Prader-Willi Syndrome
cases in Malaysia:

src: Bernama, 2025

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PWS Body Map
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General General
Marfan Marfan
PWS PWS
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Eye
Heart
Lung
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Hormonal imbalance affects reproductive development, making natural fertility difficult.

Rapid weight gain and low muscle mass increase the risk of developing type 2 diabetes.

Obesity and low muscle tone strain the heart, raising the chance of heart-related complications.

Excess body weight and abnormal hormone regulation contribute to high blood pressure.

Weak muscles and excess fat around the chest make breathing and sleep-related breathing disorders common.

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PWSManagement Hormone Therapy Supportive Therapy PWSMonitor
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src: OfficialMRDS2025

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OI Cases in Malaysia:

src: Rare Disease Malaysia 2024

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OI Body Map
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General General
Marfan Marfan
PWS PWS
OI OI
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Eye
Heart
Lung
Joint
Spine

Weak tooth structure leads to easy chipping, discoloration, and early wear.

Curved spine (scoliosis/kyphosis) can worsen mobility and affect breathing and organ function.

Abnormal or fragile ear bones interfere with sound transmission.

Loose joints and weak connective tissue increase the risk of dislocations and chronic pain.

Chest wall deformities and spinal curvature reduce lung space, making breathing difficult.

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OITherapy Assistive Care Orthopedic Interventions OiMedication
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